Business




1. End-to-End High-Throughput Omics Data Analysis

  • Raw Data Quality Control
    • Automated QC pipeline: integrated FastQC and MultiQC; machine-learning–based outlier sample detection.
    • Generates detailed reports with improvement suggestions.
  • Read Alignment & Quantification
    • Supports RNA-seq (Hisat2, STAR), DNA-seq (BWA, Bowtie2), etc., with optimized parameters and parallel scheduling.
    • C++-reengineered alignment core for large-scale sequencing data.
  • Differential Expression & Functional Annotation
    • Differential gene selection: DESeq2, edgeR, combined with in-house batch effect correction module.
    • Enrichment analysis: GO, KEGG, Reactome, cross-database comparison.
  • Single-Cell & Spatial Transcriptomics
    • Single-cell preprocessing: Cell Ranger, Scanpy, Seurat.
    • Cell subpopulation identification & trajectory inference: Monocle, PAGA.
    • Spatial transcriptome integration and visualization.
  • Multi-Omics Data Integration
    • Multi-view learning & network biology methods: MOFA, DIABLO.
    • Construct gene–protein and metabolic pathway networks to uncover potential biomarkers.

2. Platform & Software Engineering Services

  • Pipeline Automation
    • Reproducible pipelines with Nextflow, Snakemake; supports containerization (Docker, Singularity).
    • Cluster scheduling & cloud deployment (AWS, Alibaba Cloud, Huawei Cloud).
  • Web Interaction & Visualization
    • Front end: Vue.js, React with interactive charts (ECharts, Plotly).
    • Back end: Python (Django/Flask), Node.js + Express.
    • Databases: MySQL, PostgreSQL, MongoDB for large-scale time-series storage.
  • Knowledge Base & Knowledge Graphs
    • Build structured KG: gene–disease–drug relationship networks.
    • In-house reasoning engine with natural language query support.
  • C++ Tool Refactoring & Acceleration
    • Low-level optimization of key algorithms (alignment, clustering, network analysis).
    • GPU acceleration (CUDA), multithreading, SIMD support.

3. Biosafety & Biointelligence Support

  • Synthetic Biology Safety Screening
    • Automated DNA risk scanning: toxin genes, resistance genes, pathogenicity islands.
    • In-house threat prediction models combining literature mining and experimental data.
  • Policy Consultation & Technical Review
    • Provide biosafety policy recommendations and feasibility reports for regulatory agencies.
    • Assist synthetic biology companies with risk assessment and compliance audits.
  • Emergency Monitoring & Early Warning
    • Real-time monitoring platform integrating public and experimental databases to trigger alerts.
    • Global sequence database connectivity and cross-region outbreak surveillance.

4. Academic & Training Support

  • Project Design & Grant Applications
    • Assist with proposal writing and experimental/data analysis planning.
    • Provide sample size calculations and statistical design advice.
  • Manuscript Guidance
    • Results visualization: high-quality figure creation (ggplot2, Plotly).
  • Workshops & Training
    • Hands-on courses in Python/R bioinformatics.
    • Deep learning and omics analysis seminars.
    • Combined live online and in-person training.